Research Article

[Retracted] Yiqi-Huoxue Granule (YQHX) Downregulates Prothrombotic Factors by Modulating KLF2 and NF-κB in HUVECs following LPS Stimulation

Figure 3

YQHX inhibits LPS-induced PAI and TF expression through KLF2. (a) HUVECs were incubated with YQHX (0.25 and 1.25 mg/ml) or ST (3 μM) for 3 h followed with LPS (25 μg/ml) stimulation for 12 h. (b) HUVECs were infected with Lenti-GFP or Lenti-KLF2 for 24 h. (c) HUVECs were preinfected with Lenti-GFP or Lenti-KLF2, followed by LPS (25 μg/ml) stimulation for 12 h. Cell lysates were then prepared, and Western blot analysis was performed to determine the expressions of KLF2, PAI-1, and TF. Data are expressed as (). vs. control and vs. group with 25 μg/ml LPS.
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