Bidens pilosa Extract Administered after Symptom Onset Attenuates Glial Activation, Improves Motor Performance, and Prolongs Survival in a Mouse Model of Amyotrophic Lateral Sclerosis

Figure 2

Effect of MBP on the survival of G93A mice. Mice were orally administered with injection water (vehicle) or MBP, starting at a late symptomatic stage (15 weeks old). (a) Survival curve of G93A mice treated with vehicle or MBP, analysed by Kaplan-Meier analysis with the Mantel-Cox log-rank test (-10, ). The arrow indicates the start of vehicle or MBP administration. (b) The graph shows the maximum lifespan of G93A mice treated with vehicle or MBP. Values represent the . Statistical significance was determined by unpaired Student’s -test. (-10).

(a)

(b)