Bidens pilosa Extract Administered after Symptom Onset Attenuates Glial Activation, Improves Motor Performance, and Prolongs Survival in a Mouse Model of Amyotrophic Lateral Sclerosis

Figure 3

Effect of MBP on the motor performance of G93A mice. Mice were orally with administered injection water (vehicle) or MBP, starting at a late symptomatic stage (15 weeks old). Motor performance of the mice was evaluated using a rotarod apparatus. The graph depicts latency to fall from the rotarod apparatus in G93A mice treated with vehicle or MBP. Values represent the . Serial changes in motor performance were analysed with two-way ANOVA (with “drug treatment” and “weeks of age” as between-subjects’ factors) followed by Bonferroni’s post hoc test (-10). and vs. aged-matched mice treated with vehicle.