Review Article

Melatonin against Myocardial Ischemia-Reperfusion Injury: A Meta-analysis and Mechanism Insight from Animal Studies

Table 6

Metaregression of pooled estimates of infarct size.

CovariatesInfarct size
Coefficient95% CI value

Sample size2.3604350.3001453, 4.4207240.208
Species-5.111393-17.30782, 7.0850320.382
Study type2.456891-9.851739, 14.765520.673
State4.689403-0.6606213, 10.039430.081
Route of administration0.5208883-4.255456, 5.2972330.817
Duration of reperfusion0.2287274-3.982206, 4.4396610.908
Timing regimen of pretreatment3.072655-0.4711795, 6.616490.084