Circulating Levels of CILP2 Are Elevated in Coronary Heart Disease and Associated with Atherosclerosis

Figure 2

CILP2 expression in the aorta of mice and oxLDL-stimulated THP-1 macrophages. CILP2 mRNA (a) and protein (b) expression in the aorta of C57BL/6J and ApoE KO mice (). (c) IHC staining for the CILP2 expression in the aortic section of C57BL/6J and ApoE KO mice. (d, e) THP-1 macrophages incubated with oxLDL at various concentrations for 24 h. (d) CILP2 mRNA expression in cell lysates. (e) CILP2 protein levels in the culture medium. (f, g) THP-1 macrophages incubated with oxLDL (20 μg/mL) for indicated times (0–48 h). (f) CILP2 mRNA expression in cell lysates. (g) CILP2 protein levels in the culture medium. Data were expressed as . and vs. C57BL/6J, 0 μg/mL, or 0 h.

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