Circulating Levels of CILP2 Are Elevated in Coronary Heart Disease and Associated with Atherosclerosis

<div>CILP2 modulates the CD36 expressions <i>via</i> the PPAR<i>γ</i> signaling pathway. THP-1 macrophages were treated as in the Methods. (a) CD36, LOX-1, and SR-A mRNA expression. (b) ABCA1 and ABCG1 mRNA expression. (c) CD36 protein levels. (d) Quantitative analysis of CD36 protein levels. (e) PPAR<i>γ</i> mRNA expression. (f, g) Effects of GW9662 and rosiglitazone treatment on CD36 (f) and LOX-1 (g) mRNA expression. (h) CILP2-mediated transcriptional activation in the full-length CD36 promoter. 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Oxidative Medicine and Cellular Longevity

fig4

Figure 4

Figure 4: Circulating Levels of CILP2 Are Elevated in Coronary Heart Disease and Associated with Atherosclerosis 