Research Article

Circadian Clock and OxInflammation: Functional Crosstalk in Cutaneous Homeostasis

Figure 3

NRF2 binding to DNA antioxidant response element (ARE) in dex-synchronized HaCaT cells and arrhythmic ones chronically inflamed with LPS 1 μg/ml and exposed to O3. Samples were harvested at different time points (0, 2, and 6 hours after ozone exposure). Data are presented as of three independent experiments in triplicate. .