Research Article

Antitumor Therapy under Hypoxic Microenvironment by the Combination of 2-Methoxyestradiol and Sodium Dichloroacetate on Human Non-Small-Cell Lung Cancer

Figure 2

Wound healing assay under hypoxia of A549 cells treated with of 2-ME and/or DCA. (a) Representative images of wound healing in hypoxic and normoxic cells with 2-ME (10 μM), DCA (40 mM), and in combination 2-ME/DCA. The graphs show the percentage of wound closure. Two independent experiments were performed, and four areas were taken giving a total of sixteen photographs per treatment in (b) hypoxia and (c) normoxia. , , and .
(a)
(b)
(c)