Metabolomic Analysis Reveals That the Mechanism of Astaxanthin Improves the Osteogenic Differentiation Potential in Bone Marrow Mesenchymal Stem Cells

Table 1

Significant changes in metabolites of AST1 vs. control, AST10 vs. control, and AST10 vs. AST1.

	RT (min)	FC (AST10/C)	FC (AST1/C)	FC (AST10/AST1)	Name	Formula
147.1163	0.69	0.27	0.53	0.51	L-Lysine	C6H14N2O2
130.0839	0.72	0.22	0.61	0.36	L-Pipecolic acid	C6H11NO2
156.0744	0.73	0.14	0.26	0.54	L-Histidine	C6H9N3O2
175.1169	0.76	0.24	0.23	1.07	L-Arginine	C6H14N4O2
179.0581	0.78	0.12	0.27	0.44	D-Fructose	C6H12O6
132.0328	0.79	0.11	0.15	0.74	L-Aspartic acid	C4H7NO4
282.2554	11.01	2.15	1.21	1.77	Oleic acid	C5H7NO3
118.0892	0.95	0.36	0.56	0.65	L-Valine	C5H11NO2
148.0455	1.08	75.49	3.39	22.27	L-Methionine	C5H11NO2S
182.0824	1.17	82.51	1.87	44.18	L-Tyrosine	C9H11NO3
165.0541	1.18	15.82	1.47	10.76	2-Hydroxycinnamic acid	C9H8O3
130.0882	1.26	0.15	0.63	0.24	L-Leucine	C6H13NO2
256.2399	10.82	0.11	0.59	0.18	Palmitic acid	C9H7NO
557.3051	7.57	2.10	1.55	1.35	PC(P-17:0/0:0)	C25H52NO6P
136.0766	1.85	0.12	0.46	0.26	2-Phenylacetamide	C8H9NO
209.0926	2.17	0.28	0.49	0.59	Kynurenine	C10H12N2O3
149.0601	2.19	0.19	0.52	0.36	trans-Cinnamic acid	C9H8O2
166.0915	2.19	0.23	0.45	0.52	L-Phenylalanine	C9H11NO2
218.1052	2.78	0.15	0.39	0.40	Pantothenic acid	C9H17NO5
279.1355	3.51	0.10	0.35	0.28	Prolyl-tyrosine	C14H18N2O4
146.0628	4.09	0.17	0.34	0.50	4-Formyl indole	C9H7NO
205.1034	4.09	0.20	0.29	0.71	L-Tryptophan	C11H12N2O2
118.0676	4.09	0.23	0.28	0.83	Indole	C8H7N
493.3525	8.78	2.33	1.50	1.56	PC(21:4(6Z,9Z,12Z,15Z)/0:0)	C29H52NO7P