Research Article
Metabolomic Analysis Reveals That the Mechanism of Astaxanthin Improves the Osteogenic Differentiation Potential in Bone Marrow Mesenchymal Stem Cells
Table 2
Pathway analysis of different significant changes in metabolites of AST1 vs. control, AST10 vs. control, and AST10 vs. AST1.
| | Pathway name | Match status | | -Log() | Holm | FDR | Impact |
| | Aminoacyl-tRNA biosynthesis | 10/75 | | 22.796 | | | 0.11268 | | Nitrogen metabolism | 5/39 | | 11.145 | 0.0011417 | | | | Phenylalanine metabolism | 5/45 | | 10.426 | 0.0023129 | | 0.32518 | | Phenylalanine, tyrosine, and tryptophan biosynthesis | 4/27 | | 9.6249 | 0.005087 | 0.0013213 | 0.008 | | Pantothenate and CoA biosynthesis | 3/27 | 0.0014641 | 6.5265 | 0.11127 | 0.021742 | 0.18014 | | Beta-alanine metabolism | 3/28 | 0.0016306 | 6.4188 | 0.1223 | 0.021742 | 0.0 | | Biotin metabolism | 2/11 | 0.0038039 | 5.5717 | 0.28149 | 0.043473 | 0.20325 | | Valine, leucine, and isoleucine biosynthesis | 2/27 | 0.02232 | 3.8023 | 1.0 | 0.2232 | 0.0265 | | Tryptophan metabolism | 3/79 | 0.029564 | 3.5212 | 1.0 | 0.24582 | 0.16587 | | Lysine biosynthesis | 2/32 | 0.030727 | 3.4826 | 1.0 | 0.24582 | 0.09993 | | Valine, leucine, and isoleucine degradation | 2/40 | 0.046347 | 3.0716 | 1.0 | 0.33707 | 0.02232 |
|
|
