IKK Epsilon Deficiency Attenuates Angiotensin II-Induced Abdominal Aortic Aneurysm Formation in Mice by Inhibiting Inflammation, Oxidative Stress, and Apoptosis

Figure 4

IKKε deficiency diminished a proinflammatory response. Representative images of immunofluorescence staining for (a) CD68, (b) TNFα, (c) MCP1, and (d) IL6 of the aortic wall in Apoe^−/− versus Apoe^−/−IKKε^−/− mice following 28 days of saline or Ang II infusion , respectively. Quantification shown in the right panels. (e) TNFα, MCP1, and IL6 expression in aortic tissue samples detected by ELISA. vs. Apoe^−/−IKKε^−/− mice, vs. Apoe^−/−IKKε^−/− mice.

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