Decoding Aging: Understanding the Complex Relationship among Aging, Free Radicals, and GSH

Scheme 1

Synthesis of 3,5-dimaleimylbenzoic acid (3,5-DMB). Stage 1: 3,5-diaminobenzoic acid was reacted with maleic anhydride. Stage 2: cyclization of the precursor maleamide was achieved through dehydration with anhydrous sodium acetate to provide 3,5-DMB.