Research Article

The Calcilytic Drug Calhex-231 Ameliorates Vascular Hyporesponsiveness in Traumatic Hemorrhagic Shock by Inhibiting Oxidative Stress and miR-208a-Mediated Mitochondrial Fission

Figure 2

Effect of Calhex-231 on survival and hemodynamic parameters in rats with THS: (a, b) Kaplan-Meier survival curve and survival time (); (c–f) hemodynamics, including mean arterial pressure (MAP), left intraventricular systolic pressure (LVSP), and maximal change rate in left intraventricular pressure (±dp/dtmax) (). compared with the sham-operated group; #, ## compared with the LR group. Sham: sham-operated; LR: lactated Ringer’s solution; Cal: Calhex-231; B: baseline; S: shock.
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