Research Article

Interplay between Nox2 Activity and Platelet Activation in Patients with Sepsis and Septic Shock: A Prospective Study

Table 2

Comparison of parameters of the redox status and platelet function among healthy controls, septic patients who survived, and those who died during 30 days after the septic episode.

VariablesSeptic patients who survived ()Septic patients who died ()

Platelet aggregation (%)66.5 (58.5-71.5)73 (60-80)0.166
Serum thromboxane B2 (pmol/L)129.5 (120-193.75)190 (132.5-220)0.094
Serum sNox2-dp (pg/mL)20.5 (18-28)29 (19-32.5)0.309
Serum H2O2 scavenger (HBA) (%)45 (29.25-53.5)35 (24.5-52.5)0.619

Nox: NADPH oxidase; HBA: hydrogen peroxide breakdown activity; sNox2-p: soluble NOX2-derived peptides.