Direct Peritoneal Resuscitation with Pyruvate Protects the Spinal Cord and Induces Autophagy via Regulating PHD2 in a Rat Model of Spinal Cord Ischemia-Reperfusion Injury

<div>We detected the expression of PHD2 in both mRNA and protein levels of SH-SY5Y cells, as displayed in (a) the expression of PHD2 is decreased in SH-SY5Y cells treated with OGD; the expression of PHD2 was further downregulated in the SH-SY5Y cells in the group of pyruvate, while as shown in (b), the results exhibited the expression of PHD2 of SH-SY5Y cells treated with OGD is increased with the time of reoxygenation. 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Oxidative Medicine and Cellular Longevity

fig10

Figure 10

Figure 10: Direct Peritoneal Resuscitation with Pyruvate Protects the Spinal Cord and Induces Autophagy via Regulating PHD2 in a Rat Model of Spinal Cord Ischemia-Reperfusion Injury 

Figure 10 | Direct Peritoneal Resuscitation with Pyruvate Protects the Spinal Cord and Induces Autophagy via Regulating PHD2 in a Rat Model of Spinal Cord Ischemia-Reperfusion Injury 