Direct Peritoneal Resuscitation with Pyruvate Protects the Spinal Cord and Induces Autophagy via Regulating PHD2 in a Rat Model of Spinal Cord Ischemia-Reperfusion Injury

<div>SCIR increased mRNA expression of the HIF-1<i>α</i> signal pathway, which could be further upregulated after Pyr-PDS treatment. (a–d) mRNA expression of HIF-1<i>α</i>, BNIP3, Rheb, and mTOR. (e) mRNA expression of PHD. (f) Protein expression of PHD2 and summarized data of protein expression. 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Oxidative Medicine and Cellular Longevity

fig6

Figure 6

Figure 6: Direct Peritoneal Resuscitation with Pyruvate Protects the Spinal Cord and Induces Autophagy via Regulating PHD2 in a Rat Model of Spinal Cord Ischemia-Reperfusion Injury 

Figure 6 | Direct Peritoneal Resuscitation with Pyruvate Protects the Spinal Cord and Induces Autophagy via Regulating PHD2 in a Rat Model of Spinal Cord Ischemia-Reperfusion Injury 