Huangbai Liniment Accelerated Wound Healing by Activating Nrf2 Signaling in Diabetes

Figure 7

The components of HB liniment which affected Nfe2l2 and its downstream differentially expressed genes (DEs) were identified through Network pharmacology analysis. Specifically, 54 components in HB liniment were identified with 21 components from Cortex Phellodendri, 18 components from Forsythia suspensa, 9 components from Taraxacum mongolicum Hand.-Mazz, 5 from Lonicera japonica Thunb., and 7 from Scolopendridae. Some components generated from multiple Chinese medicine. Red hexagons indicated the Chinese medicine, blue triangles indicated the components of HB, blue dots indicated drug targets of components from HB liniment, and red dots indicated Nfe2l2 and its downstream DEs.