Research Article
Opuntiol Prevents Photoaging of Mouse Skin via Blocking Inflammatory Responses and Collagen Degradation
Figure 6
Effect of opuntiol on UVA-induced inflammatory protein expression in mouse skin. (a) The expression pattern of IL-6, TNF-α, COX-2, iNOS, and VEGF was analyzed by immunohistochemistry. Twenty-four hours following the last UVA irradiation, the mouse was sacrificed; the dorsal skin was used for immunohistochemistry. Representative photomicrographs (20x) illustrate IL-6, TNF-α, COX-2, iNOS, and VEGF expression in the mouse skin. (b) Densitometry analysis of IL-6, TNF-α, COX-2, iNOS, and VEGF expression in UVA and/or opuntiol-treated mouse skin. The histogram data was measured by Magnus Pro software, and the data were presented as a percentage of total tissue area. The data represent from three independent experiments, and values not sharing a common marking ( and #) differ significantly at (DMRT).
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