Phytosome Loading the Combined Extract of Mulberry Fruit and Ginger Protects against Cerebral Ischemia in Metabolic Syndrome Rats

Figure 8

Effect of various doses of PMG on the expression of PPARγ in the cerebral cortex was detected by Western blotting. (a) Representative western blot showing the levels of PPARγ. (b) Relative density of PPARγ. Data are presented as (/group). ^aaa values < 0.001; compared between naïve control rats which received normal diet and vehicle, and metabolic syndrome+MCAO rats which received HCHF, MCAO, and vehicle, ^bbb values < 0.001; compared between sham rats which received HCHF, sham operation, and vehicle, and metabolic syndrome+MCAO rats which received HCHF, MCAO, and vehicle and , , values < 0.05, 0.01, and 0.001, respectively; compared to metabolic syndrome+MCAO rats which received HCHF, MCAO, and vehicle. ND: normal diet; HCHF: high-carbohydrate high-fat diet; MCAO: middle cerebral artery occlusion; vitamin C: the vitamin C at a dose of 250 mg.kg^-1 BW; piracetam: the piracetam at a dose of 250 mg.kg^-1 BW; PMG 50, PMG 100, and PMG 200: the phytosome containing the combined extract of mulberry fruit and ginger at doses of 50, 100, and 200 mg.kg^-1 BW, respectively.

(a)

(b)