Melatonin Antagonizes Nickel-Induced Aerobic Glycolysis by Blocking ROS-Mediated HIF-1α/miR210/ISCU Axis Activation

Figure 9

Schematic indicating the role of melatonin in antagonizing nickel-induced aerobic glycolysis. Melatonin prevents the activation of the HIF-1α-controlled regulation axis through mitigating the disturbance of ROS on PHD. For more details, see Discussion.