lncRNA 00312 Attenuates Cell Proliferation and Invasion and Promotes Apoptosis in Renal Cell Carcinoma via miR-34a-5p/ASS1 Axis

Figure 1

Biological features of lncRNA 00312. (a) Relative expression of lncRNA 00312 in different RCC cell lines (). HK2: human HK2 renal proximal tubular epithelial cells on half of normal renal epithelial cells; A498: human renal epithelial cell carcinoma on half of RCC cells; ACHN: human renal adenocarcinoma cell on half of RCC cells; 786-O: human clear cell RCC on half of RCC cells; 769-P: human renal adenocarcinoma cell on half of RCC cells; ns: not significant. (b) The expressive abundance of lncRNA 00312 in different tissues of mice was detected via RT-PCR analysis (). ns: not significant. (c) The expression of lncRNA 00312 was decreased in RCC tissues compared to normal tissue (). (d) Location of lncRNA 00312 was examined via extracting specific subcellular fractions from HK2 cell line (). and versus respective control; ns: not significant.

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