lncRNA 00312 Attenuates Cell Proliferation and Invasion and Promotes Apoptosis in Renal Cell Carcinoma via miR-34a-5p/ASS1 Axis

Figure 3

Function of RCC cell lines was detected after inhibiting lncRNA 00312. (a) Inhibition of lncRNA 00312 was verified via real-time PCR (). NC: cells transfected empty vector as negative control. (b) Inhibition of lncRNA 00312 increased cell proliferation in A498 and ACHN cell lines (). NC: cells transfected empty vector as negative control. (c) Inhibition lncRNA 00312 promoted cell invasion in A498 and ACHN cell lines (). NC: cells transfected empty vector as negative control. (d, e) Cell apoptosis was decreased after inhibiting lncRNA 00312 indicated by TUNEL staining () and Western blot analysis (). NC: cells transfected empty vector as negative control. , , and versus respective control.

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