lncRNA 00312 Attenuates Cell Proliferation and Invasion and Promotes Apoptosis in Renal Cell Carcinoma via miR-34a-5p/ASS1 Axis
Table 1
Association between lncRNA 00312 expression and clinicopathological characteristics in 47 renal cell carcinoma patients.
Variable
lncRNA 00312 expression
value
Low expression ()
High expression ()
Age (years)
0.151
0.881
<60
12
14
0.010
0.920
≥60
10
11
Gender
Male
13
17
0.402
0.526
Female
9
8
Pathological grade
I–II
6
15
5.071
0.024
III–IV
16
10
Lymph node involvement
NO-N1
9
11
0.046
0.830
N2-NX
13
14
Distant metastasis
Absent
8
10
0.065
0.798
Present
14
15
Tumor size
T1-T2
8
17
4.704
0.030
T3-T4
14
8
TNM stage
I-II
7
16
4.850
0.028
III-IV
15
9
ACR (mg/g)
-0.178
0.860
<30
14
16
0.078
0.781
≥30
8
9
eGFR (mL/min/1.73m2)
0.484
0.631
≥60
16
18
0.074
0.786
<60
6
7
Cr (μmol/L)
-0.107
0.916
<82.1 (F)/97.0 (M)
18
20
0.046
0.831
≥82.1 (F)/97.0 (M)
4
5
CysC (mg/L)
-0.115
0.909
<1.09
17
18
0.006
0.938
≥1.09
5
7
Note: Statistical value by an independent samples -test. The others were values by a chi-square test. eGFR: estimated glomerular filtration rate; ACR: urine albumin-creatinine ratio; CysC: cystatin C; Cr: creatinine; F: female; M: male.