Verapamil Inhibits Mitochondria-Induced Reactive Oxygen Species and Dependent Apoptosis Pathways in Cerebral Transient Global Ischemia/Reperfusion

<div>Effects of verapamil on transient global I/R-induced apoptotic neurodegeneration. Representative photomicrographs of TUNEL staining and cell counting. (a) Representative images of the TUNEL-positive cell (arrows) were obtained from sections prepared from the animals in control, I/R, I/R+NaCl, and I/R+Ver groups. (b) DAPI nuclear staining was indicated overall in the cellular morphology of the TUNEL sections. (c) Treatment rats with verapamil significantly reduced the TUNEL-positive cell compared to I/R and I/R+NaCl groups. 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Oxidative Medicine and Cellular Longevity

fig5

Figure 5

Figure 5: Verapamil Inhibits Mitochondria-Induced Reactive Oxygen Species and Dependent Apoptosis Pathways in Cerebral Transient Global Ischemia/Reperfusion 

Figure 5 | Verapamil Inhibits Mitochondria-Induced Reactive Oxygen Species and Dependent Apoptosis Pathways in Cerebral Transient Global Ischemia/Reperfusion 