A Novel Molecular Mechanism of IKKε-Mediated Akt/mTOR Inhibition in the Cardiomyocyte Autophagy after Myocardial Infarction

Figure 6

IKKε mediates cardiomyocyte autophagy through the Akt/mTOR pathway. (a, b) Representative western blots and quantitative results of phosphorylation and total protein levels of AKT and mTOR in WT and KO mice at 2 weeks after MI or sham operation ( for each group). , . (c, d) Representative western blots and quantitative results of phosphorylation and total protein levels of AKT and mTOR in H9c2 cells under starvation injury. , , . (e, f) Representative western blots and quantitative results of phosphorylation and total protein levels of AKT and mTOR in H9c2 cells after the rescue of IKKε.

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