Potential Protective Effect of Dietary Intake of Non-α-Tocopherols on Cellular Aging Markers Mediated by Tumor Necrosis Factor-α in Prediabetes: A Cross-Sectional Study of Chinese Adults

Table 2

Spearman’s correlations of different Toc isoforms with markers of cellular aging, oxidative stress, and inflammation in various glucose tolerance status.

	Total Toc	α-Toc	β-/γ-Toc	δ-Toc
NGT ()
LTL	0.15	-0.19	0.16	0.18
mtDNAcn	0.11	-0.12	0.13	0.13
TNF-α	-0.21	0.20	-0.22	-0.28
IL-6	-0.03	0.02	-0.04	-0.03
8-OHdG	0.04	-0.04	0.04	0.06
SOD	-0.10	0.24	-0.13	-0.23
GR	0.00	0.03	0.03	0.01
Pre-DM ()
LTL	0.11	-0.30	0.14	0.16
mtDNAcn	0.04	-0.19	0.06	0.08
TNF-α	-0.32	0.19	-0.33	-0.37
IL-6	0.02	0.15	-0.01	-0.05
8-OHdG	-0.11	0.07	-0.12	-0.10
SOD	-0.13	0.11	-0.14	-0.17
GR	0.06	0.08	0.05	0.03
DM ()
LTL	0.13	-0.18	0.14	0.20
mtDNAcn	-0.05	-0.02	-0.05	-0.05
TNF-α	-0.08	0.10	-0.12	-0.11
IL-6	0.09	0.10	0.07	0.09
8-OHdG	-0.11	-0.10	-0.10	-0.05
SOD	-0.05	0.15	-0.07	-0.06
GR	0.03	-0.03	0.02	0.04

and . Abbreviations: NGT—normal glucose tolerance; pre-DM—prediabetes; DM—diabetes mellitus; Toc—tocopherol(s); LTL—leukocyte telomere length; mtDNAcn—mitochondrial DNA copy number; TNF-α—tumor necrosis factor-α; IL-6—interleukine-6; SOD—superoxide dismutase; GR—glutathione reductase.