Research Article

Potential Protective Effect of Dietary Intake of Non-α-Tocopherols on Cellular Aging Markers Mediated by Tumor Necrosis Factor-α in Prediabetes: A Cross-Sectional Study of Chinese Adults

Table 3

Spearman correlations of different Toc isoforms with markers of cellular aging, oxidative stress, and inflammation in different groups of prediabetic individuals.

Total Tocα-Tocβ-/γ-Tocδ-Toc

IFG ()
LTL0.23-0.390.260.27
mtDNAcn0.18-0.370.200.39
TNF-α-0.390.35-0.42-0.55
IL-6-0.020.17-0.10-0.11
8-OHdG0.120.040.140.13
SOD-0.05-0.04-0.04-0.10
GR0.02-0.020.040.01
IGT ()
LTL0.05-0.180.060.09
mtDNAcn0.10-0.120.120.02
TNF-α-0.26-0.06-0.27-0.21
IL-60.050.07-0.01-0.00
8-OHdG-0.200.09-0.24-0.08
SOD-0.120.12-0.09-0.11
GR0.110.070.060.03
IFG+IGT ()
LTL0.00-0.35-0.000.07
mtDNAcn-0.22-0.10-0.20-0.27
TNF-α-0.250.24-0.25-0.23
IL-60.040.200.07-0.01
8-OHdG-0.400.12-0.38-0.44
SOD-0.280.21-0.31-0.25
GR0.020.210.030.08

and . Abbreviations: Toc—tocopherol(s); IFG—impaired fasting glucose; IGT—impaired glucose tolerance; LTL—leukocyte telomere length; mtDNAcn—mitochondrial DNA copy number; TNF-α—tumor necrosis factor-α; IL-6—interleukine-6; SOD—superoxide dismutase; GR—glutathione reductase.