Triterpenoid Saponin AG8 from Ardisia gigantifolia stapf. Induces Triple Negative Breast Cancer Cells Apoptosis through Oxidative Stress Pathway

Figure 6

Effects of AG8 on phosphorylation of ERK and AKT in TNBC Cells. (a) BT549 and MDAMB-157 cells were treated with AG8 (1.0 and 1.5 μM) with or without NAC (4 mM) for 24 h, and protein expression was analyzed using Western blotting. (b) Volume intensity of band relative to matched total AKT and ERK band. Data were presented as of three independent experiments. and compared to the DMSO group; ^## and ^### compared to the AG8 group.

(a)

(b)