Methane-Rich Saline Alleviates CA/CPR Brain Injury by Inhibiting Oxidative Stress, Microglial Activation-Induced Inflammatory Responses, and ER Stress-Mediated Apoptosis

Figure 4

MRS inhibited microglial activation in the hippocampus after CA/CPR: (a) TMEM119 immunohistochemical staining, (b) CD68 immunohistochemical staining, and (c) Iba1 immunofluorescence to assess microglial activation status; (d) quantification of TMEM119 relative intensity area (%); (e) quantification of CD68 relative intensity area (%); (f) activated microglial relative intensity area (%). Data were reported as the . The statistical significance was assessed by the one-way ANOVA test ( and vs. sham control group; and ^# vs. MRS control group; ^& and ^$ vs. CPR+NS group).

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