Research Article
[Retracted] Oxidized LDL Disrupts Metabolism and Inhibits Macrophage Survival by Activating a miR-9/Drp1/Mitochondrial Fission Signaling Pathway
Figure 2
Inhibition of Drp1-related mitochondrial fission attenuates macrophage death induced by ox-LDL. (a) Cell viability was measured through the CCK-8 assay after ox-LDL and siRNA/Drp1 treatments. (b) LDH release assay was used to detect the concentration of LDH in the medium after ox-LDL and siRNA/Drp1 treatments. (c, d) TUNEL staining was used to analyze apoptosis rates in macrophages in response to LDH and siRNA/Drp1 treatments. (e, f) Caspase-3 expression was detected through immunofluorescence after ox-LDL and siRNA/Drp1 treatment. .
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