[Retracted] Oxidized LDL Disrupts Metabolism and Inhibits Macrophage Survival by Activating a miR-9/Drp1/Mitochondrial Fission Signaling Pathway

Figure 6

ox-LDL regulates Drp1-related mitochondrial fission through miR-9. (a) Transcription of miR-9 in response to ox-LDL treatment. (b–d) Mitochondrial morphology was observed using immunofluorescence. (e, f) A qPCR assay was used to measure transcription of Fis1 and Drp1 in macrophages after ox-LDL treatment. (g) Cell viability was measured in a CCK-8 assay after ox-LDL and miR-9 mimic treatments. (h, i) ELISA was used to measure GSH and SOD activity. (j, k) A qPCR assay was used to measure IL-6 and MCP1 levels in macrophages. .

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