Increased Expression of BIRC2, BIRC3, and BIRC5 from the IAP Family in Mesenchymal Stem Cells of the Umbilical Cord Wharton’s Jelly (WJSC) in Younger Women Giving Birth Naturally
Table 2
Expression levels of the BIRC2, BIRC3, and BIRC5 genes in subgroups depending on the pregnant age, umbilical cord blood pH, and method of delivery.
Gene
Group
Mean RQ
Median
SD
SE
value
Age
BIRC2
≤34 years
42
9.29
4.54
13.02
2.03
0.002
>34 years
13
2.02
1.82
1.24
0.36
BIRC3
≤34 years
42
6.38
2.46
7.31
1.17
0.0003
>34 years
13
0.45
0.27
0.40
0.12
BIRC5
≤34 years
42
1.48
1.27
3.63
0.57
0.047
>34years
13
0.87
0.96
0.57
0.16
Umbilical cord blood pH
BIRC2
≤7.3
25
11.88
5.57
15.92
3.18
0.049
>7.3
30
3.96
2.74
3.82
0.76
BIRC3
≤7.3
25
7.12
1.87
8.71
1.82
0.08
>7.3
30
3.63
0.75
4.51
0.92
BIRC5
≤7.3
25
0.65
0.44
0.64
0.11
0.001
>7.3
30
2.54
0.37
5.45
1.32
Type of delivery
BIRC2
ND
19
13.40
6.00
17.22
4.06
0.009
CS
36
4.68
2.80
6.28
1.06
BIRC3
ND
19
7.17
2.46
7.63
1.85
0.07
CS
36
4.00
0.73
6.35
1.11
BIRC5
ND
19
2.45
0.21
5.31
1.25
0.048
CS
36
0.69
0.40
0.69
0.12
Sex of newborn
BIRC2
F
25
5.01
2.35
5.64
1.11
0.074
M
30
10.51
4.31
14.83
2.71
BIRC3
F
25
3.67
0.71
5.77
1.15
0.085
M
30
8.12
2.17
12.34
2.38
BIRC5
F
25
1.40
0.44
3.84
0.75
0.612
M
30
1.93
0.40
3.91
0.70
ND: natural delivery; CS: cesarean section. The Mann–Whitney test.
