Leukocyte Telomere Length Independently Predicts 3-Year Diabetes Risk in a Longitudinal Study of Chinese Population

Table 2

Differences of clinical characteristics at the 3-year time point between progressors and nonprogressors.

Characteristics at 3-year time point	Progressors ()	Nonprogressors ()	value
BMI (kg/m^2)			0.901
WC (cm)			0.550
WHR			0.424
HbA1c (%)			0.011
FPG (mmol/L)			0.018
PG120min (mmol/L)			<0.001
FINS (mIU/L)			0.049
INS120min (mIU/L)			0.162
FCP (ng/mL)			0.075
CP120min (ng/mL)			0.027
TG (mmol/L)			0.111
TC (mmol/L)			0.738
HDL-C (mmol/L)			0.340
LDL-C (mmol/L)			0.464
Cr (μmol/L)			0.644
UA (μmol/L)			0.924
HOMA-IR			0.010
HOMA-β			0.392

Abbreviations: NGT—normal glucose tolerance; BMI—body mass index; HbA1c—glycosylated hemoglobin A1c; WC—waist circumference; WHR—waist hip ratio; FPG—fasting plasma glucose; PG—postload plasma glucose during OGTT; FINS—fasting insulin; FCP—fasting C-peptide; TC—total cholesterol; TG—total triglyceride; HDL-C—high-density lipoprotein cholesterol; LDL-C—low-density lipoprotein cholesterol; UA—uric acid; Cr—creatinine; LTL—leukocyte telomere length; mtDNAcn—mitochondrial DNA copy number; TNF-α—tumor necrosis factor-α; IL-6—interleukine-6; 8-OHdG—8-hydroxy-2-deoxyguanosine; SOD—superoxide dismutase; ISSI-2—insulin secretion-sensitivity index-2.