HSP70 Inhibition Leads to the Activation of Proteasomal System under Mild Hyperthermia Conditions in Young and Senescent Fibroblasts

Figure 2

Effects of mild hyperthermia on proteasome activity in young and senescent fibroblast cells. Cells were treated as described in Materials and Methods, and proteasome activity was measured in ATP-stimulated conditions. MCA liberation was measured for 30 min, and data were normalized to min and mg protein. Data are expressed as . vs. PD:25A. ^& vs. PD:58A ().