MicroRNA Dysregulation in the Hippocampus of Rats with Noise-Induced Hearing Loss

Table 2

The differentially expressed miRNAs in noise-induced hearing loss rats and their predicted target genes.

Transcript ID (miRNA name)

Regulation

Microarray

qRT-PCR

Predicted target genes

FC

value

FC

SD

value

rno-miR-758-5p

Up

1.86

0.028

2.23

0.14

<0.001

Bend4

Creb1

Creb5

Adcy6

Kcnj9

Pten

rno-miR-210-5p

Up

1.84

0.025

2.52

0.21

<0.001

Bend4

Creb1

Creb5

Kcnj9

Pten

rno-miR-370-5p

Up

1.80

0.042

1.85

0.04

<0.001

rno-miR-652-5p

Up

1.69

0.033

2.01

0.11

<0.001

Bend4

Creb1

Creb5

Adcy6

Kcnj9

rno-miR-3544

Up

1.61

0.048

2.73

0.27

<0.001

Bend4

Creb1

Creb5

Adcy6

Pten

rno-miR-128-1-5p

Up

1.61

0.048

2.29

0.08

<0.001

Bend4

Adcy6

Kcnj9

Pten

rno-miR-665

Up

1.60

0.023

1.66

0.06

<0.001

rno-miR-188-5p

Up

1.56

0.046

1.73

0.03

<0.001

Bend4

Pten

rno-miR-874-5p

Up

1.53

0.022

1.9

0.04

<0.001

Bend4

Creb1

Creb5

Adcy6

Kcnj9

rno-miR-448-3p

Down

0.09

0.017

0.18

0.004

<0.001

Rps6ka5

Nfatc3

Rictor

Spred1

Cdh4

Cdh6

Dvl3

Rcyt1b

rno-miR-204-5p

Down

0.16

0.015

0.35

0.01

<0.001

Rps6ka5

Nfatc3

Rictor

Spred1

Cdh4

Cdh6

Dvl3

Rcyt1b

rno-miR-204-3p

Down

0.28

0.032

0.41

0.01

<0.001

Rps6ka5

Nfatc3

Rictor

Spred1

Cdh4

Cdh6

Dvl3

Rcyt1b

rno-miR-140-5p

Down

0.58

0.043

1.63

0.04

<0.001