Early-Life Exposure to Low-Dose Cadmium Accelerates Diethylnitrosamine and Diet-Induced Liver Cancer

Figure 6

Inflammation-related protein expression in the peritumor liver tissue. Protein expression of phosphorylation and total NF-κB (a), phosphorylation and total STAT3 (b), VCAM (c), NLRP3 (d), and IL-1β (e) in male mouse peritumor liver tissue was detected, and α-tubulin was used as the loading control for western blot assay. Quantitative data were normalized to the control and expressed as (). and , Con-Can vs. control; ^# and ^##, Cd-Can vs. Con-Can. NF-κB: nuclear factor-kappa B; STAT3: signal transducer and activator of transcription 3; VCAM: vascular cell adhesion molecule-1; NLRP3: NOD-, LRR-, and pyrin domain-containing protein 3; IL-1β: interleukin-1β; SEM: standard error of the mean.

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