<i>Saccharomyces boulardii</i> Ameliorates Dextran Sulfate Sodium-Induced Ulcerative Colitis in Mice by Regulating NF-<i>κ</i>B and Nrf2 Signaling Pathways

<div><i>S. boulardii</i> alleviated pathological alterations in ulcerative colitis. (a) Representative images of colon injury shown by hematoxylin and eosin (HE) staining (Magnification: ×400; Scale bars: 20 <i>μ</i>m). Arrows indicated the infiltration of neutrophils and monocytes in mucosa. (b) Histopathological score on colons. (c) Colonic MPO level. (d) Representative colon images of colon cell apoptosis. (e) Quantification of TUNEL positive cell number/field. <span class="nowrap"><svg height="8.8423pt" id="M15" style="vertical-align:-0.2064009pt" version="1.1" viewbox="-0.0498162 -8.6359 32.2343 8.8423" width="32.2343pt" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink"><g transform="matrix(.013,0,0,-0.013,0,0)"><path d="M822 650H589L583 622C660 617 677 607 674 561C672 534 664 481 647 390L600 137H596L273 650H126L120 622C176 620 194 615 207 594C221 571 225 557 214 504L161 257C141 166 129 112 121 85C108 42 83 30 29 28L23 0H260L266 28C193 33 173 42 176 89C178 122 186 172 202 255L256 527H259L583 -8H612L690 390C708 481 720 535 728 558C744 603 756 619 816 622L822 650Z"></path></g><g transform="matrix(.013,0,0,-0.013,14.542,0)"><path d="M535 323V373H52V323H535ZM535 138V188H52V138H535Z"></path></g><g transform="matrix(.013,0,0,-0.013,25.805,0)"><path d="M249 635C141 635 70 555 70 471C70 401 114 353 179 316C143 294 106 267 90 252C68 231 45 202 45 157C45 50 130 -12 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Oxidative Medicine and Cellular Longevity

fig2

Figure 2

Figure 2: <i>Saccharomyces boulardii</i> Ameliorates Dextran Sulfate Sodium-Induced Ulcerative Colitis in Mice by Regulating NF-<i>κ</i>B and Nrf2 Signaling Pathways 

Figure 2 | Saccharomyces boulardii Ameliorates Dextran Sulfate Sodium-Induced Ulcerative Colitis in Mice by Regulating NF-κB and Nrf2 Signaling Pathways 