Exercise-Linked Irisin Prevents Mortality and Enhances Cognition in a Mice Model of Cerebral Ischemia by Regulating Klotho Expression

<div>Stroke patients showed a positive correlation between irisin and klotho concentration in their CSF. The CSF irisin concentration (a) and klotho concentration (b) were detected by ELISA. There was no correlation between the CSF irisin concentration and the CSF klotho concentration for controls (c). At the same time, there was a positive correlation between the CSF irisin concentration and the CSF klotho concentration for stroke patients (d). Stroke patients also showed a positive correlation between the CSF irisin concentration and their cognition (e). 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Oxidative Medicine and Cellular Longevity

fig1

Figure 1

Figure 1: Exercise-Linked Irisin Prevents Mortality and Enhances Cognition in a Mice Model of Cerebral Ischemia by Regulating Klotho Expression 