Research Article
Preparation and Evaluation of Silymarin-Loaded Solid Eutectic for Enhanced Anti-Inflammatory, Hepatoprotective Effect: In Vitro–In Vivo Prospect
Table 2
In vivo anti-inflammatory activity of SSD in rats.
In vivo carrageenan-induced paw edema in rats (
).
| Name of group | Edema value (mL) and % of inhibition | 30 | 60 | 120 | 360 |
| Control | | | | | Carrageenan treated | # | # | # | # | Std. diclofenac sodium (10 mg/kg) | b (33.46%) | (10.52%) | (3.38%) | (0.33%) | SSD 1 : 1 | a (67.31%) | a (45.61%) | a (35.59%) | a (26.22%) | SSD 1 : 2 | a (58.36%) | a (36.84%) | a (28.81%) | b (21.31%) | SSD 1 : 3 | a (42.80%) | (21.05%) | (13.55%) | (8.33%) |
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The data is presented as . compared with control; compared with control. |