Prestroke Metformin Use on the 1-Year Prognosis of Intracerebral Hemorrhage Patients with Type 2 Diabetes
Table 1
Demographic characteristics and clinical information of those included ICH patientsa.
ICH
730
Sex-male, (%)
421 (57.7)
Age, median (IQR), years
65 (56-72)
< 40
15 (2.1)
40-60
244 (33.4)
> 60
471 (64.5)
Race-Chinese Han
708 (97.0)
Marital status-married
699 (95.8)
Education status-college and more
44 (6.0)
Patients with time from symptom onset to hospital arrival within 2 h
118 (16.2)
Transported to hospital by EMS
132 (18.1)
Smoking
144 (19.7)
Drinking
132 (18.1)
BMI, kg/m2
23.66 (22.01-25.53)
Systolic pressure, mmHg
159 (140-175)
Diastolic pressure, mmHg
90 (80-103)
Duration of diabetes, median (IQR), years
12 (7-18)
Comorbidities
Hypertension
651 (89.2)
Dyslipidemia
126 (17.3)
Atrial fibrillation
29 (4.0)
Coronary heart disease
31 (4.2)
Coagulopathy
18 (2.5)
Hyperhomocysteinemia
41 (5.6)
A history of stroke
31 (4.2)
TIA
11 (1.5)
Laboratory serum testing
GLU, mmol/l
8.35 (6.54-10.75)
TG, mmol/l
1.37 (0.97-1.96)
TC, mmol/l
4.47 (3.80-5.22)
LDL, mmol/l
2.57 (1.98-3.38)
HDL, mmol/l
1.12 (0.95-1.41)
HCY, umol/l
12.5 (10.4-16.9)
CRP, mg/l
5.8 (1.9-11.9)
Severity at admission
GCS
12 (8-16)
mRS
3 (1-4)
ICH volume, ml
11.8 (6.5-26.7)
Prestroke treatment
Antihypertensive treatment
505 (69.2)
Antiplatelet agents
101 (13.8)
Statins
106 (14.5)
Insulin therapy
322 (44.1)
Metformin treatment
281 (38.6)
Length of stay, days
13 (8-21)
Hospitalization costs/patient, CNY
17253 (9802-39943)
Payment style-no medical insurance
61 (8.4)
Abbreviation: ICH: intracerebral hemorrhage; GCS: Glasgow Coma Scale; mRS: Modified Rankin Scale; EMS: emergency medical service; CNY: China Yuan; IQR: interquartile ranges; TIA: transient ischemic attack. aThe continuous variables are presented as median with interquartile ranges (IQRs) and categorical variables as frequency and percentage (95% CI).
