Effects of Insomnia on Peptic Ulcer Disease Using Mendelian Randomization

Table 2

Characteristics of the studied PUD-associated SNPs in both insomnia and PUD GWAS.

SNP	Gene	EA	NA	PUD results		Insomnia results
				BETA	SE		BETA	SE
rs681343	FUT2	C	T	-0.088770	0.011169		-0.006920	0.005108	0.18
rs2976388	PSCA	G	A	0.086730	0.011318		0.004309	0.005152	0.40
rs10500661	CCKBR	T	C	-0.101570	0.013439		0.004008	0.006322	0.53
rs147048677	MUC1	C	T	-0.152180	0.022310		—	—	—
rs78459074	MUC6	A	G	0.115348	0.018241		0.002804	0.008030	0.73
rs34074411	GAST	C	T	-0.072050	0.011397		-0.010940	0.005242	0.04
rs687621	ABO	A	G	0.073539	0.012116		-0.007970	0.005474	0.13
rs9581957	CDX2	C	T	-0.069730	0.011819		0.001601	0.005474	0.77

PUD: peptic ulcer disease; EA/NA: effect allele/no effect allele; BETA: effect size; SE: standard error of the effect size; : values indicate genome-wide significance in GWAS.