The Dual Effect of Abnormal Serum Uric Acid on Intervertebral Disc Degeneration
Table 3
The baseline characteristics, SUA level, and rate of IDD of 10 groups.
Characteristics
Deciles of SUA
value
D1
D2
D3
D4
D5
D6
D7
D8
D9
D10
No. of subjects
Total
138
139
135
139
138
140
136
137
138
135
Male
87
82
85
85
85
88
86
80
86
83
Female
53
51
54
53
53
54
53
51
54
52
Gender, male, (%)
Total
25 (18.1%)
27 (19.4%)
46 (34.1%)
75 (54.0%)
96 (69.6%)
91 (65.0%)
114 (83.8%)
115 (83.9%)
128 (92.8%)
130 (96.3)
<0.001
Age (years), mean (SD)
Total Male Female
43.0 (8.4)
44.0 (8.1)
42.2 (9.0)
42.7 (8.5)
39.7 (8.5)
38.1 (8.0)
37.0 (8.9)
35.9 (8.5)
36.1 (8.5)
38.1 (8.9)
<0.001
43.2 (7.8)
44.2 (7.9)
40.6 (8.7)
37.7 (8.0)
37.9 (8.0)
35.3 (8.8)
35.3 (8.7)
36.3 (8.4)
37.0 (8.1)
38.5 (9.5)
<0.001
43.0 (7.9)
43.5 (8.5)
44.5 (8.4)
44.0 (8.7)
41.3 (8.9)
41.4 (9.8)
40.3 (9.1)
39.6 (9.0)
39.5 (8.0)
37.4 (8.6)
<0.001
SUA (μmol/l), mean (SD)
Total
194.1 (24.6)
240.3 (9.6)
268.8 (7.5)
294.1 (7.0)
319.8 (7.7)
344.8 (7.2)
370.9 (7.8)
397.6 (8.1)
434.7 (15.8)
527.3 (57.9)
<0.001
Male
240.6 (30.6)
391.9 (7.7)
317.3 (7.1)
340.2 (6.5)
362.9 (5.5)
383.0 (6.0)
403.0 (6.6)
426.9 (8.8)
469.4 (15.1)
554.1 (56.6)
<0.001
Female
173.0 (24.9)
208.6 (5.3)
228.3 (5.0)
244.8 (4.2)
258.8 (3.6)
273.9 (5.1)
293.2 (6.3)
318.0 (9.0)
346.4 (8.5)
409.6 (46.6)
<0.001
LDH (%)
Total
81 (58.7%)
76 (54.7%)
63 (46.7%)
68 (48.9%)
67 (48.6%)
63 (45.0%)
61 (44.9%)3
58 (42.3%)
66 (47.8%)
88 (65.2%)
0.003
Male
50 (57.5%)
43 (52.4%)
45 (52.9%)
35 (41.2%)
35 (41.2%)
36 (40.9%)
6 (41.9%)
32 (40.0%)
57 (66.3%)
53 (63.9%)
<0.001
Female
30 (56.6%)
30 (58.8%)
29 (53.7%)
32 (60.4%)
19 (35.8%)
27 (50.0%)
23 (43.4%)
22 (43.1%)
26 (48.1%)
31 (59.6%)
0.161
Data on age and SUA are given as the . Statistical analysis by one-way ANOVA test or -test. SUA: serum uric acid; IDD: intervertebral disc degeneration.