[Retracted] Osthole Attenuates Bleomycin-Induced Pulmonary Fibrosis by Modulating NADPH Oxidase 4-Derived Oxidative Stress in Mice

Figure 1

Effect of osthole (OST) on survival rate, body weight, and pulmonary injury in bleomycin- (BLM-) treated mice. Mice were intratracheal injection of BLM and then received orally administered OST daily. At 28 days after BLM treatment, mice of the four groups were sacrificed, and the lung tissues were harvested. (a) Kaplan Meier survival analysis of the mice, the Log rank (Mantel-Cox) test was used to determine significance (-20/group). (b) Body weight (BW, -20/group). (c) Hematoxylin-Eosin (H&E) staining and lung injury scores (, scale  μm). (d) Pulmonary index (ratio of lung weight and body weight, mg/g, -20/group). vs. control; ## and ### vs. BLM.

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