Influence of Maternal Infection and Pregnancy Complications on Cord Blood Telomere Length
Table 3
Associations between clinical diagnoses during pregnancy and neonatal telomere length.
Model 1: crude associations
Model 2: further adjusted for maternal demographics and newborn characteristics+
Model 3: further adjusted for maternal risk behaviors and mental component of quality of life#
Model 4: further adjusted for each other$
(95% CI)
(95% CI)
(95% CI)
(95% CI)
Maternal health complication during pregnancy
Maternal infection
-0.16 (-0.31, -0.005)
0.042
-0.17 (-0.33, -0.02)
0.027
-0.17 (-0.33, -0.02)
0.028
-0.18 (-0.33, -0.02)
0.026
Anaemia
-0.02 (-0.17, 0.14)
0.831
0.00 (-0.16, 0.15)
0.987
0.00 (-0.16, 0.16)
0.999
-0.01 (-0.17, 0.14)
0.870
Hypertension
-0.15 (-0.45, 0.16)
0.344
-0.16 (-0.47, 0.14)
0.287
-0.16 (-0.47, 0.14)
0.294
-0.17 (-0.47, 0.13)
0.269
Any two of the above diagnoses
-0.28 (-0.53, -0.04)
0.023
-0.29 (-0.53, -0.05)
0.020
-0.29 (-0.53, -0.04)
0.021
—
—
Complication at delivery
Unspecific complications
-0.08 (-0.22, 0.07)
0.287
-0.08 (-0.22, 0.06)
0.258
-0.08 (-0.23, 0.06)
0.260
-0.09 (-0.23, 0.06)
0.232
Low birthweight
0.03 (-0.29, 0.35)
0.869
0.03 (-0.29, 0.35)
0.842
0.03 (-0.29, 0.36)
0.834
0.00 (-0.32, 0.33)
0.976
Neonatal jaundice
-0.12 (-0.33, 0.10)
0.294
-0.10 (-0.32, 0.12)
0.366
-0.10 (-0.32, 0.12)
0.369
-0.11 (-0.33, 0.11)
0.325
Any two of the above diagnoses
-0.14 (-0.44, 0.16)
0.352
-0.15 (-0.45, 0.15)
0.317
-0.15 (-0.45, 0.14)
0.314
—
—
Maternal infection x unspecific complications at delivery
-0.23 (-0.41, -0.06)
0.010
-0.25 (-0.42, -0.07)
0.006
-0.25 (-0.42, -0.07)
0.007
—
—
-0.17 (-0.72, 0.37)
0.533
-0.17 (-0.71, 0.38)
0.543
-0.16 (-0.71, 0.38)
0.556
—
—
-0.43 (-0.85, -0.01)
0.045
-0.45 (-0.88, -0.02)
0.040
-0.45 (-0.88, -0.02)
0.040
—
—
+Further adjusted for mother’s age, educational level, employment status, and infant’s sex; #further adjusted for history of smoking, being drunk, drug usage of the mothers, and the mothers’ mental component of quality of life; $further adjusted for each other’s health complications.
