[Retracted] Ginsenoside Rg3 Alleviates Antithyroid Cancer Drug Vandetanib-Induced QT Interval Prolongation

Figure 8

The effect of Gin Rg3 on vandetanib-induced inhibition of hERG channels in HEK293 cells. (a) Representative hERG current traces in HEK293 cells. (b) Representative hERG current trace at +30 mV by treatment of control, vandetanib 2 μM, and vandetanib 2 μM along with the Gin Rg3 3 μM group. (c–e) I-V curve of hERG tail current, deactivation of hERG tail current, and hERG step current of control, vandetanib 2 μM, and vandetanib 2 μM with the Gin Rg3 3 μM group (). Compared with control, and . ^#Compared with 2 μM vandetanib, ^# and ^##.

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