Downregulation of the Proton-Activated Cl- Channel TMEM206 Inhibits Malignant Properties of Human Osteosarcoma Cells

Figure 1

TMEM206 is overexpressed in OC tissues and cell lines. (a) The protein expression of TMEM206 in osteosarcoma tissues and paired para-tumor tissues were determined by using of WB (). (b, c) IHC and WB results indicated TMEM206 expression was significantly elevated in patients with advanced stage (, , , as comparing with para-tumor tissue group, respectively). (d) The expression of TMEM206 in osteosarcoma cell lines contrasted to hFOB 1.19 (, as comparing with hFOB 1.19 group, ^##, as comparing with SAOS2 group). GAPDH was used as an internal control. The data are represented as in (a, c) and represented as in (d).

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