Erythrocyte Fraction in Thrombi Is Increased with Serum Iron by Influencing Fibrin Networks via Oxidative Stress

Figure 5

Correlation of the oxidative stress level and tightness of fibrin networks in vitro. (a) Components of the modified pressure-driven system and the principle of measuring fibrin clot permeability. (b) values of fibrin clots in 0.9 mM H₂O₂ () were significantly lower than those of fibrin clots in 0.6 mM H₂O₂. values of fibrin clots in 0.6 mM H₂O₂ () were significantly lower than those of fibrin clots in 0.3 mM H₂O₂. values of fibrin clots in 0.3 mM H₂O₂ () were significantly lower than those of fibrin clots in 0 mM H₂O₂ (). values decreased significantly with increasing H₂O₂ concentration. Results are expressed as , ; ; .

(a)

(b)