MCC950, the NLRP3 Inhibitor, Protects against Cartilage Degradation in a Mouse Model of Osteoarthritis

Figure 7

Bioinformatic analysis of MCC950 target genes and pathways. (a) KEGG pathway enrichment analysis of MCC950 target genes. (b) Interaction network diagram of MCC950 target genes. (c) Intersection of MCC950 KEGG pathways and OA-related pathways (Veen Diagram). (d) Top 6 pathways in intersection pathways (KEGG enrichment chord chart). (e) Centrality evaluation and chromosomal determination of hub genes of MCC950. Loci, connections, and name of the MCC950 target gene are shown on the outermost edge, and the lines that each gene connects represent the specific chromosome on which it is located.

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