CaMK II Inhibition Attenuates ROS Dependent Necroptosis in Acinar Cells and Protects against Acute Pancreatitis in Mice

Figure 1

CaMK II was persistently highly expressed in the pancreatic tissues of AP mice. (a) Representative HE staining and immunohistochemistry images for p-CaMKII expression of pancreatic tissues in magnifications 400x. Scar  μM. each time point. (b) Levels of oxidative stress products (CAT, MDA, and GSH) of pancreas. each group. (c) p-CaMK II positive rate of immunohistochemistry images in the pancreas. (d) Protein levels of p-CaMK II and RIP3 in pancreatic tissues were analyzed by Western blotting. (e) CaMK II and GAPDH were used as a control for protein loading, respectively. (b–e) each time point. , , , and .

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