Research Article
CaMK II Inhibition Attenuates ROS Dependent Necroptosis in Acinar Cells and Protects against Acute Pancreatitis in Mice
Figure 2
KN93 mitigated the severity of caerulein-induced AP in mice. (a) Representative HE staining of pancreatic tissues in magnifications 100x and 400x. Scar μM. (b, c) The pathological scores of pancreatic tissues. (d) Serum levels of amylase and lipase. (e) The levels of GSH, MDA, and CAT in the pancreatic tissues. (f) The serum levels of TNF-α, IL-1β, IL-6, and MCP-1 was detected by ELISA. each group. and . L, M, and H represent low-dose (5 mg/kg), medium-dose (10 mg/kg), and high-dose KN93 (20 mg/kg).
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